While the world may be clamoring for a cure to a certain disease, it might wind up being more profitable for you to work on a new blood pressure medication. With a style reminiscent of the classic вЂњtycoonвЂќ games and Theme Hospital, Big Pharma also confronts the uncomfortable realities of being in the business of pharmaceutical production. Big Pharma is actually two games layered over each other: ItвЂ™s a business sim where you need to keep your drug company profitable, and a production puzzle about efficiently creating production lines. Maybe the вЂњPharma BroвЂќ should have put some time in with this game before he got in hot water for raising the price of a life-saving medication by 4,000%. Edition which comes included on the cartridge. Plus, if youвЂ™re new to the Puzzle & Dragons franchise, you can start out with the simpler, but no less charming Super Mario Bros. YouвЂ™ll have to focus on the elemental affinities of your enemies and the gems you use for your attacks, while managing skill point use and buildup.

Using the 3DSвЂ™ touchscreen, youвЂ™ll rearrange gems in a grid, but hereвЂ™s the neat part: as you use the stylus to move gems into groups of three, youвЂ™ll drag them through the other gems on the board, which you can bump into other groups in order to create combos. YouвЂ™ll do this by assembling a team of helpers and monsters, each of which has a unique set of combat skills. In Puzzle & Dragons Z, your job is to reassemble a world being torn apart. What looks initially like a straightforward match-three style game is actually two complete games, both with a lot of depth and uniqueness. #7 Puzzle & Dragons Z + Puzzle & Dragons Super Mario Bros. Splice is also very nicely presented, with a modern minimalist UI, a slick microscopic look, and meditative ambient music. ItвЂ™s delightfully tricky to predict the ways that the little cells will interact with each other, and the puzzles often center on thinking several moves ahead in order to successfully complete. Each puzzle, or вЂњsequence,вЂќ in the game has you start with a certain number of cells that you have to connect, split, and fuse in order to match a target diagram for an organism. Moving the action to the scale of the petri dish, Splice is a puzzle game about bacteria. While it never gets too complicated, thereвЂ™s enough challenge to make each solution satisfying. Puzzles start off very simple, introducing the language of the game, but ramp up in difficulty as you progress into later levels. Instead, you move objects around in a physics-based environment in order to manipulate doors, move energy beams, and operate machinery. Unmechanical could be described as a вЂњpuzzle platformer,вЂќ except for the fact that as a propeller-equipped little robot, you donвЂ™t really do any jumping. The Fates can destroy bits of the land you create if theyвЂ™re angered, but youвЂ™ve also got a menu of disasters to unleash yourself if you get tired of building and want to see a bit of the old death вЂn destruction.ДЄs Alfred said, вЂњSome men just want to watch the world burn.вЂќ #9 Unmechanical: Extended Edition (PS4, Xbox One)

ThereвЂ™s a вЂњcreativeвЂќ mode where you can take as long as you like to create whatever kind of world you desire, or a challenging timed mode, where a five-minute timer counts down the seconds to apocalyptic oblivion. #10 Fate Tectonics (PC)ДЇate Tectonicsis kind of a god game, except youвЂ™re not the god вЂ“ you place tiles in order to create a world, but the combinations you create can either please or anger the powerful вЂњFatesвЂќ who float around your land. Let us know which of these is your favorite, or tell us about one weвЂ™ve missed in the comments section below. But people are still making great puzzle games, and here are our picks for the Top Ten Puzzle Games of 2015. ThereвЂ™s not a lot of AAA development put into puzzle games these days, though, and a lot of the puzzle games that do come out seem to be made for mobile devices. TheyвЂ™re designed to poke at our brains and stretch our reasoning powers in new and interesting ways, and coming up with solutions can be incredibly satisfying (who hasnвЂ™t punched the air in victory after working out a tricky Portal test chamber?). Puzzle games represent what may be modern gamingвЂ™s link to the most ancient eras of human history: spatial and logic puzzles have been with us for millennia.

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